当谈到胶原蛋白 - 您如何服用?在某些聚会上,人们甚至喝抗衰老补充剂的镜头,通常是龙舌兰酒 - 尽管后者可能不建议在寻找年轻,桃红色的皮肤中。胶原蛋白是体内最丰富的蛋白质,形成脚手架,有助于维持我们的皮肤和肌肉骨骼系统的结构完整性。简而言之,胶原蛋白有助于保持我们的皮肤丰满,关节和骨骼坚固,头发和指甲健康。它变得如此珍贵,以至于一些皮肤科医生建议“银行”它 - 早日投资于我们的胶原蛋白供应,因此当不可避免的情况发生时,我们有多余的东西。是的。不可避免的。老化。叹。当我们到达20多岁时,我们的胶原蛋白供应自然会平均每年减少约1%。其下降速度取决于我们接触太阳,饮食和压力水平等因素。但是,是否有可靠的科学可以说补品可以补充我们减少的供应?如果是这样,将其进入我们的身体的最佳方法是什么?金伯利·史密斯(Kimberlie Smith)大约六个月前开始服用胶原蛋白。这位33岁的年轻人在2024年“创伤一年”之后开始使用它。她的儿子过早出生,由于压力,三个孩子的母亲说她的皮肤受到了“巨大的命中”。她每天用热带味道凝胶,使用海洋胶原蛋白(源自鱼类的类型)。金伯利说:“我的皮肤肯定越明亮,更清晰,而且自从我开始服用以来,我的头发从未看起来更好。” “作为一个被剥夺睡眠的母亲,这绝对有所作为。”基于伦敦哈雷街(Harley Street)的顾问皮肤科医生艾玛·韦奇沃思(Emma Wedgeworth)说,虽然有一些研究表明口服胶原蛋白会产生影响,但她仍然持怀疑态度。她说,胶原蛋白可以穿越我们的身体(不是最简单的任务)的想法,而我们需要的地方可能是一厢情愿的想法。首先,它必须通过肠道而不会完全分解。胶原蛋白是一个大分子,因此公司现在已经开始将其分成较小的碎片 - 胶原蛋白肽 - 也称为水解胶原蛋白。即使这种胶原蛋白(现在以较小的形式)有更大的机会穿过肠壁并进入血液,但它仍然还有很长的路要走。“防晒霜,健康的饮食,如果您抽烟,停止。”这些会比胶原蛋白补充剂更大。”自闭症社区的成员除了研究外,自闭症的人需要接受和支持。永久性的风湿病学家和皮肤科医生将基于岛上的岛屿。真正令人兴奋的早期发现可能是对妇女的疾病的良好态度的一步。 NHS基金会吗?它必须到达皮肤才能产生影响,并且很容易滑落以支撑体内其他器官。这是一个宝贵的资源。 “对此几乎没有可靠的证据,但是有一种理论认为,由于我们的皮肤是具有'最快流动'的器官,因此可能更有可能在其他器官上方使用这些胶原蛋白肽。”那时,您可能会增加皮肤细胞中胶原蛋白的增加。这一切似乎非常复杂,而且不确定。它可能会让您问:使用胶原蛋白霜呢?他们直接进入皮肤,所以他们不再有机会到达需要的地方吗?韦格沃思女士的简单答案是“不,”。 “胶原蛋白只会坐在皮肤的外层上,它不会到达真皮 - 这是中层。”胶原蛋白补充剂有三种不同的类型:海洋(来自鱼),牛(来自牛)和素食主义者。在这三个中,皮肤科医生建议海洋,如果您要口服胶原蛋白。这是因为它包含更多的1型胶原蛋白 - 这是五种类型中最常见的胶原蛋白,并且是赋予我们皮肤细胞结构的一种胶原蛋白,并且在我们的骨骼,肌腱和结缔组织的健康中起着至关重要的作用。 Wedgeworth女士说,素食胶原蛋白是最不可能的。胶原蛋白是一种动物来源的蛋白质,因此这些产物实际上不是由胶原蛋白制成的,而是含有一系列氨基酸和维生素。 “我被困住了。”阿里·沃森(Ali Watson)告诉我,她指着厨房里的牛胶原蛋白粉。 “是的,这对我来说是对的,好吧,这是给汤米的。”我看着接下来的细长的棕色猎犬,灰须在他的鼻子上戳出来。他在承认中抬起眉毛。阿里(Ali)是一位神经狂热者,她自己的承认“对给药很了解”,感觉就像现在她已经开始服用胶原蛋白了,她无法停止 - 她也不能停止将其交给狗。 “几年前,我开始把它当作粉末。起初,这与我的外观无关,而是关于我的关节,我想保护它们,因为我做了很多重量。”阿里不确定她是否发现关节有任何不同,但她注意到其他地方的变化。 “我的皮肤感觉更加发光,头发感觉更浓密,指甲感觉更强壮。”我瞥了一眼汤米(Tommy),他对他的狗碗似乎比任何粉末补品都更感兴趣。“我知道,这似乎很生气,”阿里说:“但是汤米似乎较慢,夏天之前的热情降低了,所以我想我会尝试他的狗胶原蛋白。”我想看看它是否可以帮助他的关节 - 他现在已经变老了。而且他有点亮,但这可能只是因为天气又变得更冷,而且他的热和昏昏欲睡。您可能会在倒下时将它们带走,然后再来一次 - 这可能与补充剂无关。 “但是到那个阶段,你不能冒险停止。”柴郡NHS Trust的顾问皮肤科医生Faisal Ali教授说,消费者和临床医生面临的问题之一是补充研究中相互矛盾的信息和冲突的利益。最近的一项相对较小的研究将健康行业资助的研究与没有同样利益冲突的研究进行了比较。尽管行业资助的研究表明,胶原蛋白补充剂可显着改善皮肤的水合,弹性和皱纹,但没有从制药公司那里获得资金的胶原蛋白补充剂显示对皮肤没有影响。阿里教授说,由行业资助的研究并不是“天生的糟糕”,而是如此多样化。但是他说,缺乏强大的证据表明口头和局部胶原蛋白具有任何实质性作用。因此,如果我可以在20多岁的时候开始返回时间,开始喝酒和银行胶原蛋白,现在我会问他更流畅,更年轻的皮肤,我问他吗?他说,可能不是。它不会持续那么长时间 - 我们没有胶原蛋白商店的橱柜,我们可以浸入其中。但是,阿里教授认为,我们可以使用特殊的技术(例如激光胶原蛋白刺激和微针刺激)来增强胶原蛋白输出并保持皮肤中的弹性。这意味着使用许多微小的专业针头或激光对我们的皮肤造成小伤口,从而鼓励修复过程,从而触发新的胶原蛋白形成。但这并不便宜。您可能会为一次会议支付最高300英镑的费用。还有昂贵的替代方案吗?阿里教授说:“您可以为皮肤做的最好的事情是使用体面的防晒霜。我们知道太阳对衰老的皮肤产生了巨大影响。
Collagen: Do you drink it? Inject it? Rub it on your skin? And does it work?
When it comes to collagen - how do you take yours? There are parties where people even drink shots of the anti-ageing supplement, often followed by a hefty tequila - though the latter is probably not recommended in the quest for youthful, peachy skin. Collagen is the most abundant protein in the body, and forms the scaffolding that helps maintain the structural integrity of our skin and musculoskeletal system. In short, collagen helps to keep our skin plump, our joints and bones strong, and our hair and nails healthy. It's become so treasured that some dermatologists recommend "banking" it - investing in our collagen supply early so we have surplus when the inevitable happens. Yes. The inevitable. Ageing. Sigh. Our collagen supply naturally starts to decrease, on average around 1% a year, as we reach our mid to late 20s. The speed of its decline depends on factors like our exposure to the sun, diet, and stress levels. But is there credible science to say supplements can replenish our dwindling supply? And if so, what's the best way of getting it into our bodies? Kimberlie Smith started taking collagen about six months ago. The 33-year-old began using it after a "traumatic year" in 2024. Her son was born prematurely, and as a result of stress, the mother-of-three says her skin took a "huge hit". She uses marine collagen, the type derived from fish, in a tropical-flavoured gel she drinks every day. "My skin definitely seems to be brighter and clearer, plus my hair has never looked better since I started taking it," Kimberlie says. "As a sleep deprived mother, it's definitely made a difference." Emma Wedgeworth, a consultant dermatologist based on London's Harley Street, says while there is some research to suggest taking collagen orally has an impact, she remains sceptical. She says the idea that collagen can make its journey through our body - not the easiest of quests - and land exactly where we need it to be is probably wishful thinking. For a start, it has to get through the gut without being completely broken down. Collagen is a large molecule so companies have now started to break it up into smaller pieces - collagen peptides - otherwise known as hydrolysed collagen. Even though this collagen - now in its smaller form - has a better chance of making its way through the intestinal wall and into the bloodstream, it still has a long way to go. It has to reach the skin to have an impact, and it could just as easily slip off to support other organs in the body. It's a valuable resource. "There is little reliable evidence on this, but there is a theory that because our skin is the organ with the 'fastest turnover' of cells, it might be more likely to use these collagen peptides above other organs." And that's when you might get an increase in collagen being made in the skin cells. That all seems very complicated - and uncertain. It may leave you asking: what about using collagen creams? They're going directly onto the skin, so won't they stand more chance of getting where they need to be? "No," is Ms Wedgworth's simple answer. "The collagen will just sit on the outer layer of your skin, it won't reach the dermis - which is the middle layer." There are three different types of collagen supplements: marine (from fish), bovine (from cows), and vegan. Of the three, the dermatologist recommends marine if you are taking collagen orally. This is because it contains more type 1 collagen - the most common of the five types and the one that gives structure to our skin cells, as well as playing a crucial role in the health of our bones, tendons and connective tissues. Vegan collagen is the least effective, says Ms Wedgeworth. Collagen is an animal-derived protein, so these products are not actually made of collagen, and instead contain a range of amino acids and vitamins. "I'm trapped," Ali Watson tells me as she points to packs of bovine collagen powder in her kitchen. "Yes, this one is for me and well, this one is for Tommy." I look at the slender brown hound next me, grey whiskers poking out round his nose. He lifts an eyebrow in acknowledgement. Ali, a neuroanaesthetist who, by her own admission, "knows a lot about dosing", feels like now she's started taking collagen, she can't stop - and nor can she stop giving it to her dog. "I started taking it as a powder a couple of years ago. At first, it wasn't about my appearance, it was about my joints, I wanted to protect them because I do a lot of weight-lifting." Ali's not sure that she's noticed any difference with her joints, but she has noticed a change elsewhere. "My skin feels like it glows more, my hair feels thicker and my nails feel stronger." I glance down at Tommy, who seems more interested in his dog bowl than any powdered supplements. "I know, it seems mad," Ali says, "but Tommy seemed a bit slower, a bit less enthusiastic just before summer, so I thought I would try him on dog collagen. "I wanted to see if it could help with his joints - he's getting old now. And he is a bit brighter, but that might just be because the weather's got colder again and he's less hot and lethargic." Ali's not completely convinced the supplement is making a difference, and it's costing her £60 a month to ensure she and Tommy get their daily dose. But she says she now can't stop. "That's the thing with these supplements," the 46-year-old says, "life does have its ups and downs. You might take them when you're on a down, then things pick up again - and it might have very little to do with the supplements. "But by that stage, you can't risk stopping." Professor Faisal Ali, a consultant dermatologist at Mid Cheshire NHS Trust, says one of the issues consumers and clinicians face is the amount of conflicting information and conflicting interests in supplement research. A recent, relatively small, study compared research funded by the wellness industry to studies that did not have the same conflict of interest. While industry-funded studies suggested collagen supplements significantly improved skin hydration, elasticity and wrinkles, those that did not receive funding from pharmaceutical companies revealed no effect on skin. Prof Ali says industry-funded studies are not "inherently bad", it's just such a varied picture. But he says there is a lack of robust evidence to suggest oral and topical collagen have any substantial effect. So if I could turn back time and start drinking and banking collagen in my 20s, would I have smoother, more youthful skin now, I ask him? Probably not, he says. It doesn't stay in the body for that long - we haven't got a collagen store cupboard that we can just dip into. However, Prof Ali believes we can potentially boost collagen output and maintain elasticity in our skin by using special techniques such as laser collagen stimulation and microneedling. This means using a number of tiny, specialist needles or a laser to make small wounds to our skin, which then encourage a repair process, triggering new collagen formation. But that's not cheap. You could be paying up to £300 for one session. Is there a less costly alternative? "The best thing you can do for your skin," Prof Ali says, "is using decent sunblock. We know the sun has a huge impact on ageing our skin. "Sun cream, healthy diet, and if you smoke, stop. "These will have a far greater impact than collagen supplements." Members of the autism community say in addition to research, people with autism need acceptance and support. A permanent rheumatologist and dermatologist will be based on the island. The "truly exciting" early findings could be a step towards halting MS progression, a charity says. Families are elated by news of the first treatment for Huntington's disease - but when and how will the NHS fund it? Brighton & Hove Albion have released a video highlighting the importance of men talking.
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